| Date | Speaker | Topic | Host |
|---|---|---|---|
| 10/2/25 | Graham Heimberg, Genentech | P. He | |
| 10/9/25 | Jian Ma, Carnegie Mellon University | Y. Shen | |
| 10/30/25 | Rommie Amaro, UC San Diego | Kollman Lecture: | B. Shoichet & M. Grabe & J. Gross |
| 11/6/25 | Daniel Cohen, Princeton | H. Scott | |
| 11/13/25 | Eric Deeds, UC Los Angeles | W. Marshall | |
| 11/20/25 | Duncan Muir | Clements Lecture | |
| 12/4/25 | Garry Nolan, Stanford | H. Bhargava | |
| 12/11/25 | Ning Zheng, University of Washington, HHMI | Targeted Protein Degradation: Chemical Degrons and Genetic Glues | J. Taunton |
| 1/15/26 | Bruno Correia, EPFL | H. Musunuri | |
| 1/22/26 | Joshua Coon, University of Wisconsin-Madison | K. Yazdani | |
| 1/29/26 | Michael Levin, Tufts | A. Kalish | |
| 2/19/26 | Elizabeth Hillman, St. Jude Children's Research Hospital | R. Abbasi-Asl | |
| 2/26/26 | Olexandr Isayev, Carnegie Mellon University | B. Shoichet | |
| 3/5/26 | Xiao Wang, MIT | K. Yazdani | |
| 3/12/26 | Doeke Hekstra, Harvard | K. Chrispens | |
| 3/19/26 | Bradley Pentelute, MIT | K. Yazdani | |
| 4/2/26 | Elham Azizi, Columbia | R. Abbasi-Asl | |
| 4/9/26 | Susan Shao, Harvard | Modulators of protein homeostasis | J. Taunton |
| 4/16/26 | Amy Keating, MIT | L. Schnaider | |
| 4/23/26 | Sydney Shaffer, University of Pennsylvania | C. Hsiung | |
| 4/30/26 | Neil King, University of Washington | K. Estrada Alamo | |
| 5/7/26 | Georg Winter, CeMM -Research Center for Molecular Medicine | J. Pampel & S. Christine-Porak | |
| 5/21/26 | Bryan Roth, University of North Carolina | C. Nnadi | |
| 5/28/26 | Scott Prosser, University of Toronto Mississauga | A. Manglik |
| Date | Speaker | Topic | Host |
|---|---|---|---|
| 10/3/24 | Andrew Kruse, Harvard | Biophysical mechanisms of integral membrane protein function | B. Shoichet |
| 10/10/24 | Gabriel Rocklin, Northwestern | High-throughput discovery of protein stability and dynamics | W. Coyote-Maestas |
| 10/17/24 | Tarun Kapoor, Rockefeller | Chemical biology of ATPase mechanoenzymes | S. Casebeer |
| 10/24/24 | Matt Thomson, Caltech | Discovery and Design of Living Algorithms | Z. Gartner |
| 10/31/24 | Evelyn Strickland | Clements Lecture: How many cooks is too many? How neutrophils collectively decide when the kitchen is full. | O. Weiner |
| 11/7/24 | Nicholas Schork, The Translational Genomics Research Institute | Emerging Bioinformatics Strategies to Enable Precision Medicine | S. Baranzini |
| 11/14/24 | Scott Coyle, University of Wisconsin-Madison | Understanding and engineering cell biology in space and time with programmable reaction-diffusion systems | A. Alamban |
| 11/21/24 | Jared Toettcher, Princeton | Towards light-guided embryogenesis: using optogenetics and biosensors to probe developmental patterning | A. Alamban |
| 12/5/24 | Alex Holehouse, Washington University | Sequence and chemical specificity define the functional landscape of intrinsically disordered proteins | T. Kortemme |
| 12/12/24 | Alice Ting, Stanford | Braisted Lecture: Engineering proteins to map and manipulate cells | C. Craik |
| 1/9/25 | Phil Cole, Harvard | Chemical approaches to understanding lysine modifications | B. Al-Sady |
| 1/23/25 | Heng Li, Harvard | Challenges and promises of long-read sequencing | Y. Zhang |
| 1/30/25 | Lindsey Ingerman James, UNC Chapel Hill | Altering the H3 Methylation Landscape through Degradation of Methyl-Lysine Reader Proteins | D. Fujimori |
| 2/6/25 | Cristina Paulino, Heidelberg University | Think like a channel, act like a carrier - the case of SLC9C1, a sperm-specific voltage-gated Na+/H+ exchanger | M. Grabe |
| 2/20/25 | David Savage, UC Berkeley | Mechanisms and Engineering of CO2 Assimilation | D. Chen |
| 3/13/25 | Emily Hodges, Vanderbilt | Understanding short- and long-term epigenome control of gene regulation in development and disease | T. Capra |
| 3/27/25 | Qiong Yang, University of Michigan | Synthetic Growth and Patterning: Clock Energy Dissipation, Mechanical coupling, and Spatial Coordination | W. Marshall |
| 4/17/25 | Nancie Archin, UNC Chapel Hill | Chasing an HIV Cure: The Intersection of Biological Sex and Latency Reversal | A. Frankel |
| 4/24/25 | Christina Woo, Harvard | Investigation of endogenous substrates of the E3 ligase cereblon | B. Zaro |
| 5/1/25 | Josefina del Mármol, Harvard | Structural determinants of odor sensing in insects | K. Susa |
| 5/8/25 | Jennifer Prescher, UC Irvine | Imaging tools and technologies inspired by nature’s light-emitting chemistry | J. Montano |
| 5/22/25 | Parisa Hosseinzadeh, University of Oregon | Development of a novel in-silico tool for heterochiral macrocyclic design | Z. Mawaldi |
| Date | Speaker | Topic | Host |
|---|---|---|---|
| 9/28/23 | Michael Elowitz, Caltech | Synthetic circuits for multicellular systems | A. Kishishita |
| 10/5/23 | Laura Dassama, Stanford | Deciphering the molecular mechanisms of lipid trafficking in bacteria | D. Fujimori |
| 10/12/23 | Stephanie Wankowicz, Clements Lecture | Making sense of the chaos: conformational entropy and ligand binding | J. Fraser |
| 10/19/23 | Mitchell Guttman, Caltech | RNA promotes the formation of spatial compartments in the nucleus | B. Choy |
| 10/26/23 | Carrie Partch, UCSC | Lessons from an in vitro circadian clock | K. Delgado-Cunningham |
| 11/2/23 | Oliver Clarke, Columbia | Architecture of erythrocyte ankyrin complexes | K. Verba |
| 11/9/23 | Alison Ondrus, University of Illinois, Chicago | Function at the metabolite-protein interface | B. Zaro |
| 11/16/23 | Elizabeth Bess, UC Irvine | Finding Catalysts of Gut Reactions: The Gut Microbiota in Disease Onset and Treatment | Z. Gartner & P. Turnbaugh |
| 12/7/23 | Nir London, Weizman Institute | Covalent ligands - from binding to function | B. Shoichet |
| 1/11/24 | Moumita Das, RIT | TBD | W. Marshall |
| 1/18/24 | Gladstone Center for Cell Circuitry: Ronald Germain, NIH | Deciphering the Working Principles of the Immune System at the Tissue Level Using Optical Imaging and New Analytical Tools | L. Weinberger |
| 2/1/24 | Antentor Hinton, Vanderbilt | Inter-organelle contact Biology in human disease | R. Hogan |
| 2/8/24 | Chad Myers, University of Minnesota | Mapping and analysis of a global reference genetic interaction network for human cells | E. Gilbertson |
| 2/22/24 | Martin Hemberg, Harvard | Profiling the tumor microenvironment using spatial transcriptomics | N. Ahituv |
| 3/7/24 | Ronald Raines, MIT | Lessons from Collagen | V. Garda |
| 3/14/24 | Matt Pratt, USC | Build it to understand it: Uncovering the roles of O-GlcNAc in neurodegenerative diseases using protein synthesis | B. Zaro |
| 3/21/24 | Bosiljka Tasic, Allen Institute | Cell types of the adult mouse cortex: definition and experimental access | R. Abbasi Asl |
| 4/4/24 | Nozomi Ando, Cornell | Conformational Switching in a Flexible, Multi-Domain Enzyme | S. Wankowicz |
| 4/11/24 | Laura Huckins, Yale | Integrating Gene-Environment Interactions in Psychiatric Disorder Risk | Y. Chen |
| 4/18/24 | Karine Gibbs, UC Berkeley | Social dynamics in swarming colonies. | S. Warrington-Casebeer |
| 5/9/24 | Armita Nourmohammad, University of Washington | Learning the shape of protein and immune universe | H. Miller |
| 5/16/24 | Nieng Yan, Shenzhen Medical Academy of Research & Translation (SMART) | Targeting Nav channels for pain relief | R. Stroud, Host |
| 5/30/24 | HARC Speaker: Michael Summers, University of Maryland | Mechanism for control of HIV-1 transcript function and genome packaging | A. Frankel |
| 6/6/24 | Mohammad Seyedsayamdost, Princeton | Natural Product Antibiotics: Past, Present, Future | B. Shoichet |
| Date | Speaker | Topic | Host |
|---|---|---|---|
| 9/29/22 | James Ferrell, Stanford | Cytoplasmic self-organization and dynamics | L. Weinberger |
| 10/6/22 | Sergey Ovchinnikov, Harvard | Inverting protein structure prediction models to solve problems in biology | B. Orr |
| 10/13/22 | Sam Reck-Peterson, UCSD | My squid teacher: RNA recoding of the intracellular transport machinery | S. Dumont |
| 10/20/22 | Daniel Asarnow, University of Washington | Clements Lecture | Y. Cheng |
| 10/27/22 | Greg Bowman, University of Pennsylvania | Protein dynamics and energy landscape design | M. Jacobson |
| 11/3/22 | Mohammed AlQuraishi, Columbia University | OpenFold: Lessons learned and insights gained from rebuilding AlphaFold2 | B. Orr |
| 11/17/22 | Peijun Zhang, Oxford | HARC Speaker: Visualizing virus infection in cells by cryoEM | C. Craik |
| 1/12/23 | Rebecca Voorhees, Caltech | How membrane proteins get to mitochondria | A. Manglik |
| 1/19/23 | Saeed Hassanpour, Dartmouth | Deep Learning for Histopathological Characterization of Microscopy Images | B. Miao |
| 1/26/23 | Sujit Datta, Princeton, HD 160 | Life in a tight spot: How bacteria navigate crowded spaces | S. Floor |
| 2/23/23 | Tingting Yang, Columbia University | The structure and function of bestrophins | D. Minor |
| 3/2/23 | Jean-Laurent Casanova, Rockefeller, HD 160 | The human genetic and immunological determinants of life-threatening COVID-19 | W. Shen |
| 3/9/23 | John Chodera, Sloan-Kettering Cancer Center | The COVID Moonshot and beyond: Antiviral drug discovery for global equitable and affordable access | M. Smith |
| 3/23/23 | Pei Zhou, Duke | Novel Therapeutics Targeting Undruggable Protein Interfaces and Minor Conformational States | J. Gross |
| 4/6/23 | Elizabeth Villa, UCSD | Opening Windows into the Cell: Bringing structure to cell biology using cryo-electron tomography | D. Southworth |
| 4/13/23 | John Teijaro, Scripps | Myeloid reprogramming by JAK inhibition enhances checkpoint blockade therapy in mice and humans | K. Shokat |
| 4/20/23 | Jin Zhang, UCSD | Illuminating the Biochemical Activity Architecture of the Cell | X. Shu |
| 4/27/23 | Derek Lowe, Novartis | Chemical Biology: How We Got Here (And Where We Might Be Going) | M. Moore |
| 5/4/23 | Xin Jin, Scripps | In vivo Perturb-seq: scalable investigation of gene function and organ-wide action | P. Grosjean |
| 5/11/23 | Suzanne Walker, Harvard | How Bacteria Move Acyl Groups from the Cytoplasm to Extracellular Polymers | B. Zaro |
| 5/18/23 | Squire Booker, Pennsylvania State University | A Radical Solution for C(sp3)–C(sp3) Bond Formation during the Biosynthesis of Macrocyclic Membrane Lipids | D. Fujimori |
| 6/8/23 | David Shaw, DE Shaw Research | Can Computational Methods Cure What Ails Ya? Progress, Problems and Prospects | R. Kormos |
| Date | Speaker | Topic | Host |
|---|---|---|---|
| 10/7/21 | 9 AM, Chloe-Agathe Azencott, CBIO Mines ParisTech, Institut Curie, INSERM | 9 AM, Network-guided genome-wide association studies | C. Stephens |
| 10/14/21 | Carlos Bustamante, UC Berkeley | Division of Labor and Mechanism of Translocation of a Ring ATPase | M. Jaime Garza |
| 10/28/21 | Jeremy England, Georgia Tech | Self-Organization of Lifelike Behaviors | D. Rajan |
| 11/4/21 | Marco Mravic, Scripps | Clements Lecture: Membrane Protein Computational Design: biophysical principles and chemical biology tools. | B. DeGrado |
| 12/2/21 | Olga Boudker, Weill Cornell | Substrate discrimination and transport determinants in plasma membrane glutamate transporters | R. Edwards & D. Minor |
| 1/6/22 | Feng Zhang, MIT | Exploration of Biological Diversity | P. Klauser & W. Shen |
| 1/13/22 | Aaron Ring, Yale | Targeting the immune exoproteome | C. Bracken & S. Elledge |
| 1/27/22 | Negar Rostamzadeh, Google | Rethinking Values in Machine Learning Research and Practice | H. Goodarzi |
| 2/3/22 | Vanessa Ruta, Rockefeller University | Sensing scents: the structural and circuit mechanisms of olfaction | A. Manglik |
| 2/10/22 | Greg Towers, University College London | HARC Lecture: What’s so special about pandemic viruses? HIV and SARS-CoV-2 vs Innate Immunity | N. Krogan |
| 2/17/22 | David Baker, University of Washington | Protein design using deep learning | C. Bracken & P. Burroughs |
| 3/17/22 | Squire Booker, Pennsylvania State University | Moving beyond methionine synthase: New insight into cobalamin-dependent methylation reactions | D. Fujimori |
| 3/31/22 | Joanna Wysocka, Stanford University | Gladstone Center for Cell Circuitry Seminar: Transcriptional regulation and emergence of form and function during development and evolution. | L. Weinberger |
| 4/7/22 | 4 pm, Alanna Schepartz, UC Berkeley | Braisted Lecture: Reimagining the Definition of a Protein | C. Craik |
| 4/14/22 | Tanja Mittag, St. Jude Children's Research Hospital | Protein disorder, multivalency and phase separation: Implications for biological function and disease | W. Weiss |
| 4/21/22 | CANCELLED: Elizabeth Villa, UCSD | Opening Windows into the Cell: Bringing Structure into Cell Biology using cryo-electron tomography | S. Floor |
| 4/28/22 | Karlene Cimprich, Stanford | Gladstone Center for Cell Circuitry Seminar: RNA Meets DNA: Dangerous Liaisons in the Genome | L. Weinberger |
| 5/5/22 | 4 pm: Ken Dill, Stony Brook University | Peter A. Kollman Lecture: Survival of the Fittest as a principle. What drives it? What started it? | B. Shoichet |
| 5/19/22 | Liz Kellogg, Cornell University | Mechanisms driving molecular innovation: Cryo-EM studies of CRISPR-associated transposons | D. Chen |
| 6/2/22 | Jiaoyang Jiang, University of Wisconsin-Madison | Decoding sweet regulation at substrate level – implications for signaling and disease | J. Weaver |
| Date | Speaker | Topic | Host |
|---|---|---|---|
| 9/24/20 | Allison Williams, UCSF | Unraveling the mechanism of activation of the bacterial stress signaling platform | James Fraser |
| 10/1/20 | Margaret Gardel, University of Chicago | Cytoskeletal Mechanosensing by LIM domains | Dyche Mullins |
| 10/8/20 | Cole Trapnell, University of Washington | Embryo scale single-cell spatial transcriptomics | Sourav Bandyopadhyay |
| 10/22/20 | Mikhail Shapiro, Caltech | Biomolecular Ultrasound for Non-Invasive Imaging and Control of Cellular Function | Aashish Manglik |
| 11/5/20 | Pardis Sabeti, Harvard | Outbreak Response in the Genomic Age | Wren Saylor |
| 12/3/20 | Laura Kiessling, MIT | Carbohydrates as Cellular IDs | J. Braxton, D. Schwarz |
| 12/10/20 | Aviv Regev, Genentech | Co-Sponsored with the Helen Diller Cancer Center: Cell Atlases as Roadmaps to Understand Genes and Treat Disease | Jimmie Ye |
| 1/7/21 | Florentine Rutaganira, UC Berkeley | Chemical Biology in the Closest Living Relatives of Animals | Cynthia Chio |
| 1/14/21 | Donita Brady, University of Pennsylvania | Cellular and Molecular Determinants of Copper Activation of Protein Kinases in Cancer | Natalia Jura |
| 1/21/21 | Axel Brunger, Stanford | Molecular Mechanisms of Synaptic Neurotransmitter Release | Robert Edwards |
| 1/28/21 | Robert Spitale, UC Irvine | Chemical Approaches to Analyzing the Transcriptome | Stephen Floor |
| 2/4/21 | Lillian Kenner, Genentech | Clements Lecture: A Structural View of Translation Initiation using cryo-EM | Adam Frost |
| 2/11/21 | Philip Kranzusch, Harvard | Evolution of antiviral immunity | Ryan Tibble |
| 2/18/21 | Gaudenz Danuser, UT Southwestern | How shape shapes cancer cells | Tamas Nagy |
| 2/25/21 | Kevin Eggan, Harvard | Deciphering the Molecular Logic of Motor Neuron Degeneration in ALS | Lani Wu |
| 3/4/21 | David Relman, Stanford | Gladstone Center for Cell Circuitry Seminar: The response to disturbance in the human microbial ecosystem | Leor Weinberger |
| 3/11/21 | Judith Klinman, UC Berkeley | Emerging Experimental Probes of Reaction Specific Dynamical Networks that Control Enzyme Activation | Sasha Dickinson |
| 3/18/21 | Hunter Fraser, Stanford | Using hybrids to explore the evolution of complex traits | Nadav Ahituv |
| 4/1/21 | Eugene Valkov, NIH | Biochemical Studies of Messenger RNA Degradation | J. Gross |
| 4/8/21 | Kevin Haigis, Harvard | How mutations and post-translational modifications influence K-RAS networks | Sourav Bandyopadhyay |
| 4/15/21 | Lisa Jones, University of Maryland | In-Cell Protein Footprinting Coupled with Mass Spectrometry for Proteome-Wide Structural Biology | Snow Naing & Samuel Thompson |
| 4/22/21 | Vamsi Mootha, Harvard | Mitochondrial parts, pathways, and pathogenesis | Yessica Gomez |
| 4/29/21 | Demet Araç, University of Chicago | Cellular Communication via Adhesion in the Nervous System | Aashish Manglik |
| 5/6/21 | Helen Blackwell, University of Wisconsin-Madison | Chemical Interventions into Bacterial Cell-Cell Signaling | Wenqi Shen |
| 5/13/21 | Larry Hamann, Takeda Pharmaceuticals | Expanding the Druggable Genome Through Cereblon-Mediated Protein Degradation | Danica Galonic Fujimori |
| 5/20/21 | Wes Sundquist, University of Utah | HARC Lecture: Structure and Function of the HIV Capsid | Nevan Krogan |
| 6/3/21 | Vincent Tagliabracci, UT Southwestern | Expanding the kinome | Natalia Jura |
| Date | Speaker | Topic | Host |
|---|---|---|---|
| 10/3/19 | Francois Diederich, ETH Zurich | OFF TIME: 4 PM, Novartis Lecture: Molecular Recognition in Chemical and Biological Systems: Chemical Models and Biostructural Investigations | B. DeGrado |
| 10/10/19 | Hiroaki Suga, University of Tokyo | Revolutionizing the discovery process of therapeutically worthy peptides | S. Dai |
| 10/24/19 | Neville Bethel | Clements Lecture: Microscopic Elasticity: Membranes and Proteins | M. Grabe |
| 11/7/19 | Jeremy Luban, University of Massachusetts Medical School | HARC Seminar: Tales of resistance to HIV-1 and related creatures | N. Krogan |
| 11/14/19 | Sally Horne-Badonivac, University of Chicago | Going in circles gets you somewhere – signaling mechanisms that coordinate cell movements for collective migration. | S. Altschuler |
| 11/21/19 | Tobias Meyer, Stanford | Gladstone Center for Cell Circuitry Seminar: Multi-reporter live microscopy reveals how mammalian cells decide to enter or exit the cell cycle | L. Weinberger |
| 12/5/19 | Ahmad Khalil, Boston University | Computation, Memory, and Complexity: Design of Gene Regulatory Circuits in Eukaryotic Cells | H. El Samad |
| 1/9/20 | Cassandra Quave, Emory University | Ethnobotany-guided discovery of novel natural products for infectious disease | D. Julius |
| 1/23/20 | Lingyin Li, Stanford University | Understanding the anti-cancer STING pathway and harnessing it to treat metastatic cancers | S. Dai |
| 1/30/20 | Cynthia Wolberger, Johns Hopkins Medical Institute | OFF TIME: 3:30 PM, Histone ubiquitination in transcription and nucleosome dynamics. | D. Fujimori |
| 2/6/20 | Chuan He, University of Chicago | Alternate Room HD 160, RNA methylation in gene expression regulation | S. Dai, P. Klauser |
| 2/13/20 | Trey Ideker, UCSD | Interpreting the cancer genome through physical and functional models of the cancer cell | S. Bandyopadhyay |
| 2/20/20 | Debora Marks, Harvard | Learning and designing genotype to phenotype with neural machines | M. Kampmann |
| 2/27/20 | Barry Honig, Columbia | Alternate Room HD 160, The molecular basis of cell-cell recognition: Cellular patterning and nervous system wiring | T. Kortemme |
| 3/5/20 | CANCELLED: Demet Araç, University of Chicago | CANCELLED: Cellular Communication via Adhesion in the Nervous System | A. Manglik |
| 3/12/20 | CANCELLED: Mikhail Shapiro, Caltech | CANCELLED: Biomolecular Ultrasound for Non-Invasive Imaging and Control of Cellular Function | J. Fraser |
| 4/9/20 | CANCELLED: Derek Lowe, Novartis | CANCELLED: Drug Discovery From the Inside? | M. Moore |
| 4/15/20 | CANCELLED: Vamsi Mootha, Harvard | CANCELLED: Joint Seminar with BMS: TBA | G. Lewis |
| 4/23/20 | CANCELLED: Cole Trapnell, University of Washington | CANCELLED | S. Bandyopadhyay |
| 4/30/20 | CANCELLED: Vincent Tagliabracci, UT Southwestern | CANCELLED: Expanding the kinome | N. Jura |
| 5/7/20 | Polly Fordyce, Stanford | Leveraging microfluidics for high-throughput biophysics, biochemistry, and single-cell biology | S. Floor |
| 5/14/20 | CANCELLED: Gaudenz Danuser, UT Southwestern | CANCELLED | T. Nagy |
| 5/21/20 | CANCELLED: Jiaoyang Jiang, University of Wisconsin-Madison | CANCELLED | H. Wang |
| 6/4/20 | CANCELLED: Philip Kranzusch, Harvard | CANCELLED: cGAS-like enzymes in human immunity and host-microbe signaling | R. Tibble |
| Date | Speaker | Topic | Host |
|---|---|---|---|
| 9/27/18 | Gaya Amarasinghe, Washington University | Viral immune evasion mechanisms | John Gross |
| 10/4/18 | Tracy Johnson, UCLA | RNA Processing, Chromatin Modification, and the Coordinated Control of Gene Expression | Stephen Floor |
| 10/18/18 | Yuan Gao | Clements Lecture: Structural studies on ligand and lipid modulation of the capsaicin receptor, TRPV1 | Yifan Cheng & David Julius |
| 10/25/18 | Youxing Jiang, UT Southwestern | Structural Insights into the Selectivity and Gating of Organellar Two-pore Channels | Robert Stroud |
| 11/8/18 | Tom Muir, Princeton | Braisted Lecture: Inteins: Discovery, Engineering and Applications to Chromatin Biology | Charly Craik |
| 11/15/18 | Jesse Bloom, Fred Hutchinson Cancer Research Center | HARC Seminar: How genetic heterogeneity affects the outcome of viral infection in single cells | John Gross |
| 11/29/18 | Sinisa Urban, JHMI | Life in the membrane: the story of rhomboid intramembrane proteases | Aashish Manglik |
| 12/6/18 | Elizabeth Winzeler, UCSD | Using genetics and genomics to find next-generation cures for malaria | Eric Gonzalez |
| 1/10/19 | Long Cai, Caltech | Spatial genomics and dynamics by intron seqFISH | Sourav Bandyopadhyay |
| 1/17/19 | Olivia Rissland, University of Colorado, Denver | Connections between translation and mRNA decay | Stephen Floor |
| 1/24/19 | Gregory Alushin, The Rockefeller University | Cytoskeletal structural plasticity in force generation and mechanosensation | Aashish Manglik |
| 1/31/19 | Carolyn Bertozzi, Stanford | Cancer immune therapies targeting glycol-immune checkpoints | Peter Rohweder |
| 2/7/19 | Angela Brooks, UCSC | Characterizing RNA splicing alterations in cancer | Taylor Cavazos |
| 2/14/19 | Hesper Rego, Yale | Bacterial infections - one cell at a time | Seemay Chou |
| 2/21/19 | Robert Singer, Albert Einstein College of Medicine and Janelia Farm | Gladstone Center for Cell Circuitry Seminar: Following single mRNAs in living cells | Leor Weinberger |
| 2/28/19 | OFF DATE & TIME, Frances Arnold, Caltech | Kollman Lecture: Machine learning-enhanced directed evolution of enzymes and channelrhodopsins | Tom Ferrin |
| 3/14/19 | Rachel Klevit, University of Washington | From One to Many: How Ubiquitin Regulates (almost) Everything | Sasha Dickinson |
| 4/4/19 | Zan Luthey-Schulten, University of Illinois at Urbana-Champaign | Towards Simulating a Minimal Bacterial Cell: Integration of Experiment and Theory | Wallace Marshall |
| 4/25/19 | Christine Jacob-Wagner, Yale | Gladstone Instittute for Cell Circuitry Seminar: Governing and organizational principles of transcription and translation: Lessons from bacteria | Fred Chang |
| 5/2/19 | Kabirul Islam, University of Pittsburgh | Protein and Small Molecule Engineering towards an Orthogonal Chromatin Landscape | Michelle Arkin & Danica Galonic Fujimori |
| 5/9/19 | Ibrahim Cisse, MIT | Super-resolution imaging of transcription in live mammalian cells | Greyson Lewis |
| 5/16/19 | Katherine Henzler-Wildman, University of Wisconsin | Re-thinking the transport mechanism of the small multidrug efflux pump, EmrE: Does promiscuity preclude tight coupling? | Aashish Manglik |
| 5/30/19 | David Liu, Harvard | Base editing: chemistry on a target base in the genome of living cells | Susanna Elledge & Jack Stevenson |
| Date | Speaker | Topic | Host |
|---|---|---|---|
| 10/12/17 | Peng Wu, TSRI | Chemoenzymatic glycan labeling: methods and applications | Lei Wang |
| 10/26/17 | Wes Sundquist, University of Utah | HARC Seminar: Harnessing and Inhibiting the ESCRT Virus Budding Pathway | John Gross |
| 11/2/17 | Hassane Mchaourab, Vanderbilt | Principles of Energy Transduction and Alternating Access of ABC Transporters | Dan Minor |
| 11/9/17 | Arieh Warshel, USC | Kollman Lecture: How to Simulate the Action of Complex Biological Systems on a Molecular Level ? | John Gross |
| 11/16/17 | Neda Bagheri, Northwestern University | An in silico study of emergent dynamics in a cancer microenvironment | Wallace Marshall |
| 11/30/17 | Carsten Schultz, OHSU | Tools for imaging and manipulating signaling networks | Lei Wang |
| 1/11/18 | Milan Mrksich, Northwestern | Combining Arrays and Mass Spectrometry for High Throughput Discovery in Chemistry and Biology | Lei Wang |
| 1/18/18 | Andrew Myers, Harvard | Toward the discovery of next-generation antibiotics. | Ian Seiple |
| 2/1/18 | Karl Broman, University of Wisconsin- Madison | 17 years of R/qtl: developing, maintaining, and supporting scientific software | John Witte |
| 2/8/18 | CANCELLED: Carolyn Bertozzi, Stanford | CANCELLED: Cancer immune therapies targeting glyco-immune checkpoints | Peter Rohweder |
| 2/15/18 | Gurol Suel, UCSD | Metabolic oscillations and electrical signaling in biofilms | Leor Weinberger |
| 2/22/18 | Steve Quake, Stanford | Physiology and Aging Probed with Single Cell Genomics | Ruilin Tian |
| 3/1/18 | Christina Homer | Clements Lecture | |
| 3/8/18 | Thomas Kodadek, TSRI- Jupiter | Chemical tools to monitor and manipulate the proteome | Peter Rohweder |
| 4/5/18 | Jeremy Gunawardena, Harvard University | Beyond the Bacterial Paradigm in Gene Regulation | Greyson Lewis |
| 4/12/18 | Rachel Green, Johns Hopkins University | Ribosome recycling, rescue and homeostasis | Weihan Li |
| 4/19/18 | Matt Simon, Yale University | Chemistry to study the dynamics of cellular RNA populations | Kevan Shokat |
| 4/26/18 | Klaus Hahn, UNC Chapel Hill | Building proteins to peek and poke at GTPase circuits in vivo | Xiaokun Shu |
| 5/3/18 | Christopher Burge, MIT | Protein-RNA Interactions and RNA Processing | Hiten Madhani |
| 5/10/18 | Forest White, MIT | Mechanisms of therapeutic resistance revealed by quantitative functional proteomics | Natalia Jura |
| 5/17/18 | Tom Rapoport, Harvard | Mechanism of ER-associated protein degradation (ERAD) | Adam Frost |
| 5/31/18 | Andre Levchenko, Yale University | Are signaling networks Rube Goldberg machines? information processing vs. network structure | Wallace Marshall |
| Date | Speaker | Topic | Host |
|---|---|---|---|
| 9/22/16 | Grant Jensen, Caltech | Structural biology in vivo through electron cryotomography | Bill DeGrado |
| 9/29/16 | Jennifer Cochran, Stanford | Engineered Proteins for Visualizing and Treating Cancer | Bill DeGrado |
| 10/4/16 | Ruth Ley, MPI Tuebingen | Genetic determinants of the gut microbiome and links to phenotype | Svetlana Lyallina |
| 10/6/16 | Jonathan Gable | Clements Lecture: Targeting a Dynamic Protein-Protein Interface to Inhibit a Critical Herpesvirus Enzyme | Charly Craik |
| 10/13/16 | Eckhard Jankowsky, Case Western | RNA helicases in translation initiation and granule formation. | John Gross & David Weinberg |
| 10/20/16 | Yong Xiong, Yale | HIV Capsid Pattern Sensing by the Host | John Gross |
| 10/27/16 | Roberto Chica, University of Ottowa | Engineering protein conformational landscapes using multistate computational protein design | James Fraser |
| 11/3/16 | Jason Moore, University of Pennsylvania | An Automated Data Science Assistant | Ryan Hernandez |
| 11/10/16 | Ken Prehoda, University of Oregon | The ties that bind-evolution of a protein interaction domain family | Wendell Lim |
| 11/17/16 | David Eisenberg, UCLA | Braisted Lecture, Pathogenic vs. Reversible Amyloid | Charly Craik |
| 12/1/16 | Ivan Dikic, Goethe Institute | Ubiquitin and autophagy networks: learning from bacteria about neurodegeneration and cancer | Natalia Jura |
| 1/12/17 | Kimberly Reynolds, UT Southwestern | A conserved evolutionary unit in central metabolism | Yuliya Birman |
| 1/19/17 | Joachim Frank, Columbia | Time-resolved cryo-EM: first biological results with the mixing/spraying microfluidic chip. | Rahel Woldeyes |
| 1/26/17 | Gerhard Wagner | Membrane protein studies in nano discs | Daniel Asarnow |
| 2/2/17 | Eric Alm, MIT | The ecology of the human microbiome in health and disease | Leanna Morinishi |
| 2/9/17 | Dorothea Fiedler, Princeton | Elucidating the role of inositol pyrophosphates in cellular signaling | Danica Fujimori |
| 2/16/17 | Jeff Kelly, Scripps | Adapting Proteostasis to Ameliorate Degenerative Diseases Linked to Protein Aggregation | Martin Kampmann |
| 2/23/17 | James Noonan, Yale | Genetic models of human evolution | Nadav Ahituv |
| 3/2/17 | Alexander Mankin, University of Illinois at Chicago | Stopping the stopping: how one inhibitor can interfere with termination of translation in two different ways | Danica Fujimori |
| 3/9/17 | Steve Elledge, Harvard | Breaking Bad: How Aneuploidy Drives Cancer | Sourav Bandyopadhyay |
| 3/16/17 | Emily Balskus, Harvard | Chemical Discovery in the Human Microbiota | Fatima Ugur |
| 4/6/17 | George Peng Wang, Georgia State University | Chemical biology concepts and experiments for everyone | Lei Wang |
| 4/13/17 | Ron Dror, Stanford, 3 PM | 3 PM: PAK Lecture: Revealing the structural basis for GPCR drug action through atomic-level simulation. | John Gross |
| 5/11/17 | Nieng Yan, Tsinghua University | Structural investigation of voltage-gated sodium channels | Bo Huang |
| 5/18/17 | Michael Burkart, UCSD | Protein-protein interactions in acetate biosynthetic pathways. | Ryan Muir |
| Date | Speaker | Topic | Host |
|---|---|---|---|
| 9/24/15 | Hiro Furukawa, Cold Spring Harbor | Structure and Biology of NMDA receptor ion channels | Dan Minor |
| 10/1/15 | David Burkhardt | Clements Lecture | Dave Agard |
| 10/8/15 | Eric Siggia, Rockefeller | Differentiation of micropatterned human embryonic stem cell colonies recapitulates the early embryo | Matt Thomson |
| 10/15/15 | Timothy Lu, MIT | Programming Cells for Human Health Applications | Hana El-Samad |
| 10/22/15 | Andrew Ward, Scripps | High-resolution cryoEM structures of viral glycoproteins and neutralizing antibodies | Bill DeGrado |
| 10/29/15 | Chris Garcia, Stanford | Tuning cell surface receptor signaling through ligand engineering: Type I receptors versus GPCR | Jennifer Kung |
| 11/12/15 | Xuewu Zhang, UT Southwestern | Regulation mechanisms of the neuronal axon guidance receptor plexin | Natalia Jura |
| 12/3/15 | Jay Shendure, University of Washington | New methods in human genetics | Nima Emami |
| 1/7/16 | Petra Fromme, Arizona State University | Femtosecond Crystallography: A revolution in Structural Biology | Jessica Thomaston |
| 1/21/16 | Michael Gilson, UCSD | 5th Annual Peter A. Kollman Lecture: The Physical Basis of Computer-Aided Drug Design | John Gross |
| 2/4/16 | Taekjip Ha, University of Illinois Urbana-Champaign | Surprising Physics of DNA on the Genome Scale | Terri Lee |
| 2/11/16 | Alice Ting, MIT | Spatially-Resolved Proteomic Mapping of Living Cells Reveals New Proteins and Functions in the Mitochondria and Neuronal Synapse | Juan Perez Bermejo |
| 2/18/16 | Erin O'Shea, Harvard | Timekeeping by a Three Protein Circadian Clock | Jonathan Weissman |
| 2/25/16 | Michael Rosen, UT Southwestern | Physical Mechanisms of Cell Organization on Micron Length Scales | Joe Lobel |
| 3/3/16 | Carrie Partch, UCSC | Dissecting the molecular basis for circadian timekeeping | D. Fujimori |
| 3/10/16 | Tuuli Lappalainen, NYGC | Functional variation in the human genome: lessons from the transcriptome | Tara Friedrich |
| 4/7/16 | Ronen Marmorstein, U Penn | Molecular Basis for Protein Acetylation | Danica Fujimori |
| 4/14/16 | Ian Wilson, Scripps | Broad neutralization of viral pathogens | Bob Stroud |
| 4/28/16 | Debbie Nickerson, University of Washington | Lessons learned from scaling the analysis of Mendelian conditions | Tara Friedrich |
| 5/5/16 | David Savage, UC Berkeley | Fixed: Synthetic biological approaches for probing cellular physiology | James Fraser |
| 5/12/16 | Chris Voigt, MIT | Cello: A programming language for living cells | |
| 5/19/16 | Xiaowei Zhuang, Harvard | Illuminating Biology at the Nanoscale with Single-molecule and Super-resolution Imaging | Bo Huang |
| Date | Speaker | Topic | Host |
|---|---|---|---|
| 9/25/14 | Elaine Kirschke | Clements Lecture | Dave Agard |
| 10/2/14 | Phil Geissler, UC Berkeley | Quantifying the diversity of side-chain fluctuations in folded proteins | Kale Kundert |
| 10/9/14 | Hashim Al-Hashimi, Duke | Role of Nucleic Acid Dynamics in the Central Dogma of Molecular Biology | James Fraser |
| 10/16/14 | Lior Pachter, UC Berkeley | Transcriptome genetics. | Daniel Himmelstein |
| 10/23/14 | Gail Fanucci, University of Florida | Mechanisms of Drug Resistance in HIV-1 Protease Explored by EPR and NMR Spectroscopies | John Gross |
| 10/30/14 | Markus Seeliger, Stonybrook | A dynamically coupled allosteric network in the regulation of Src family kinases | Natalia Jura |
| 11/6/14 | Laura Kiessling, University of Wisconsin | Braisted Lecture: Us Versus Them: Cell Surface Glycans to Distinguish Human and Microbial Cells | Jim Wells |
| 11/13/14 | Jeff Gore, MIT | Cooperation, cheating, and collapse in microbial populations | Matt Thomson |
| 11/20/14 | Molly Przeworski, Columbia University | An evolutionary perspective on the human germline mutation rate | Tara Friedrich |
| 1/8/15 | Mark Murcko, Disruptive Biomedical | Kollman Lecture: Progress Towards Predicting Ligand Binding Free Energy | John Gross |
| 1/15/15 | Edward Marcotte, University of Texas at Austin | Evolution, the proteome, and disease | James Webber |
| 1/22/15 | Barak Cohen, Washington University in St. Louis | Why don't transcription factors get lost? | Nadav Ahituv |
| 2/5/15 | Robert Keenan, University of Chicago | Tail-anchored membrane proteins biogenesis | Bill DeGrado |
| 2/12/15 | Judith Klinman, UC Berkeley | Moving through Barriers: Unlocking the Mysteries of How Enzymes Really Work | Susan Miller |
| 2/19/15 | Anne-Claude Gingras, Lunenfeld | Kinase-phosphatase interactomes: a tale of Hippos and mulberries | Rebecca Levin |
| 2/26/15 | Samie Jaffrey, Cornell | Imaging RNA and RNA biology using RNA mimics of green fluorescent protein | David Weinberg |
| 3/5/15 | Ruth Nussinov, NIH | Signaling pathways in cancer | Diego Garrido Ruiz |
| 4/2/15 | Jennifer Doudna, UC Berkeley | CRISPR Biology: From Discovery to Application | Bill DeGrado |
| 4/9/15 | Dewey McCafferty | Lysine-Specific Histone Demethylase LSD1: Mechanism, Biology, and Emerging Role in Breast Cancer | Bill DeGrado |
| 4/16/15 | Ronald Raines, University of Wisconsin | Ribonuclease: From kcat/KM to the Clinic | Sam Pollock |
| 4/23/15 | Jeffrey Hubbell, University of Chicago | Engineering antigen presentation in immunity and tolerance | Tejal Desai |
| 4/30/15 | Vlad Denic, Harvard | Activation of Atg1 kinase by receptor-bound targets initiates selective autophagy | Jonathan Weissman |
| 5/7/15 | Jennifer Prescher | Expanding the imaging toolbox | Zev Gartner |
| 5/14/15 | Evgeny Nudler, NYU | Molecular Trafficking in Gene Control and DNA Maintenance | Leo Gendelev |
| 5/21/15 | Ming Hammond, UC Berkeley | Exploiting riboswitches to study and manipulate bacterial signaling | Danica Galonic Fujimori |
| 5/28/15 | Michael Elowitz, Caltech | An operational view of mammalian signaling and memory circuits | Brian Sharon |
| Date | Speaker | Topic | Host |
|---|---|---|---|
| 9/26/13 | Laura Lavery | Clements Lecture: Molecular asymmetry provides new insights into Hsp90 mechanism | Dave Agard |
| 10/17/13 | Richard Bonneau, NYU | Integrative computational methods for learning dynamic regulatory models: application to T-cell differentiation and function | Andrew Sczesnak |
| 10/24/13 | David Bartel, MIT | MicroRNAs and a developmental switch in the nature of translational control. | Hiten Madhani |
| 10/31/13 | Erin Carlson, Indiana University | Chemical Probes to Explore and Inhibit Bacterial Pathogenesis | Danica Galonic Fujimori |
| 11/21/13 | Dana Pe'er, Columbia University | What can you do with 40 dimensions in single cells, mapping development, signal processing and disease? | Wendell Lim |
| 1/9/14 | Wah Chiu, Baylor College of Medicine | Structures of Viruses Inside and Outside the Host Cells | Yifan Cheng |
| 1/16/14 | Kevin Healy, UC Berkeley | Disease-Specific Microphysiological Human Organ Models: the Future of Personalized Medicine? | Bruce Conklin |
| 1/23/14 | David Mooney, Harvard | Biomaterials as therapeutic cancer vaccines | Tejal Desai |
| 1/30/14 | Kate Carroll | Painting the Cysteine Chapel: New Tools to Probe Oxidation Biology | Bill DeGrado |
| 2/13/14 | Benjamin Cravatt, Scripps | Activity-based proteomics - applications for enzyme and inhibitor discovery. | Christina Fitzsimmons & Becca Levin |
| 2/20/14 | Claudio Joazeiro, Scripps | Listerin/Ltn1 links Co-translational Protein Quality Control and Neurodegeneration. | Jonathan Weissman |
| 2/27/14 | Bianxiao Cui, Stanford | Light-controlled intracellular signaling pathways in cell fate determination | Bo Huang |
| 3/13/14 | Tim Hughes, University of Toronto | Kaleidoscopic evolution of C2H2 zinc finger DNA binding | Nevan Krogan |
| 4/3/14 | Tack Kuntz, Kollman Lecture | Computation, Modeling & Evolution at UCSF: Past, Present, Future | John Gross |
| 4/10/14 | David Baker, University of Washington | Design of protein structures, functions and assemblies | Jennifer Kung & Justin Rettenmaier |
| 4/17/14 | Rama Ranganathan, UT Southwestern | The evolutionary "design" of proteins | Sara Calhoun & Diego Garrido Ruiz |
| 4/24/14 | Alexander Hoffman, UCSD | Network Dynamics as a basis for Specificity | Hana El Samad |
| 5/1/14 | Dorothee Kern, Brandeis | The evolution of kinase dynamics over 1 billion years reveals Gleevec's selectivity | James Fraser |
| 5/8/14 | Trey Ideker, UCSD | Siri of the Cell: What Biology Can Learn From The iPhone. | James Webber |
| 5/15/14 | L. Mahadevan, Harvard | A physical basis for morphogenesis? | Matt Thomson |
| 5/22/14 | Cliff Brangwynne, Princeton | Intracellular Phase Transitions and Cell Size | Dyche Mullins |
| 5/29/14 | Johan Paulsson, Harvard | Quantifying dynamics in single cells | Graham Heimberg |
| Date | Speaker | Topic | Host |
|---|---|---|---|
| 9/27/12 | Sheng Zhong, U Illinois | Comparative Epigenomics: a case study of human, mouse and pig pluripotent stem cells. | Bo Huang |
| 10/11/12 | Caleb Bashor | Clements Lecture | Wendell Lim |
| 10/18/12 | Dianne Newman, Caltech | New interpretations of ancient biomarkers: exploring the functions of (2-methyl) hopanoids, steroid analogs in bacteria | Joe Kliegman |
| 10/24/12 | Stuart Schreiber, Harvard University | Braisted Lecture, Cancer genetic dependencies targeted by small molecules | Jim Wells |
| 11/8/12 | Doug Lauffenberger, MIT | In Vivo Systems Analysis of Cell-Cell Communication and Signaling in Inflammation | Kathy Giacomini |
| 11/15/12 | Robert Lamb, Northwestern | Activating protein re-folding to cause paramyxovirus-mediated membrane fusion | Bill DeGrado |
| 11/28/12 | Greg Verdine, Harvard | Cancer Chemical Biology | Jim Wells |
| 11/29/12 | Sunney Xie, Harvard | Life at the Single Molecule Level | David Burkhardt |
| 1/10/13 | Susan Marqusee, UC Berkeley | Sequence Determinants of a Protein's Energy Landscape | Henry Lin |
| 1/17/13 | David Odde, University of Minnesota | Microtubule self-assembly kinetics | Wallace Marshall & Dyche Mullins |
| 1/24/13 | Wenying Shou, Fred Hutchinson Cancer Center | War and peace: a biological basis for population segregation and mixing | Wallace Marshall |
| 2/7/13 | Jonathan Javitch, Columbia | A tale of two substrates: a novel mechanism for neurotransmitter:sodium symport | Robert Edwards |
| 2/14/13 | Michael Levitt, Stanford | Kollman Lecture: Combinatorial Methods Solve a Difficult Structural Problem to Reveal How Chaperonins Work in Eukaryotes | John Gross |
| 2/21/13 | Bridget Carragher, Scripps | Investigating the dynamics of molecular machines using automated electron microscopy | Bob Stroud |
| 2/28/13 | David Liu, Harvard | Small-molecule and macromolecule discovery driven by evolution | Zev Gartner |
| 3/7/13 | Michael Laub, MIT | Specificity and evolution of bacterial signaling pathways. | Anthony Shiver |
| 3/14/13 | Celeste Nelson, Princeton | Physical control of tissue morphogenesis | Zev Gartner |
| 4/11/13 | Brenda Schulman, St. Jude Children's Research Hospital | Twists and Turns in Ubiquitin Conjugation Cascades | John Gross |
| 4/18/13 | Garry Nolan, Stanford | A structure for cancer and immunity at the single cell level by mass cytometry | Justin Rettenmaier |
| 4/25/13 | Adrian Keatinge-Clay, University of Texas | Visualizing and harnessing polyketide assembly lines | Bob Stroud |
| 5/2/13 | Laura Kiessling, University of Wisconsin-Madison | Probing and Perturbing the Cell's Glycan Coat | Kevan Shokat |
| 5/16/13 | Jeffrey Skolnick, Georgia Tech | Interplay of physics and evolution in the likely origin of protein biochemical function | Peter Cimermancic |
| Date | Speaker | Topic | Host |
|---|---|---|---|
| 9/29/11 | Vijay Pande | Some surprises in the Biophysics of Protein Dynamics | Emmanuel Yera, Jain Lab, Computational Student Group |
| 10/13/11 | Jure Leskovec | Computational Perspectives on the Structure and Information Flows in On-Line Networks | Michael Fischbach |
| 10/13/11 | Jure Leskovec, Stanford | Michael Fischbach | |
| 10/20/11 | BP Clements Best Thesis Talk, Anselm Levskaya | Closed Loop Optogenetics for the Study of Neural Circuitry In Vivo | Chris Voigt |
| 10/27/11 | Jim Ferrell, Stanford | Dissecting the Mitotic Trigger | Wendell Lim |
| 11/3/11 | Adam Cohen, Harvard | Bo Huang | |
| 11/17/11 | Galit Lahav, Harvard | Encoding information through protein dynamics | Wendell Lim, Center for Systems & Synthetic Biology |
| 12/1/11 | Doug Lauffenberger, MIT | Quantitative Cell Bioengineering Analysis of EGF Receptor Inhibitor Effectiveness in Cancer Therapeutics | Kathy Giacomini, QBC Sponsored |
| 12/7/11 | Tom Tuschl | Characterization of regulatory small RNAs and RNA-binding proteins | Michael McManus |
| 1/12/12 | Ivan Ovcharenko, NIH NCBI | Computational strategies for deciphering the sequence encoding of gene regulatory elements | Mee J Kim, Ahituv Lab |
| 1/19/12 | Kristala Jones Prather, MIT | Parts, Devices, and Chassis in Support of Metabolic Engineering | David Booth |
| 1/26/12 | Robert Austin, Princeton | Darwinian Evolution: Not As Slow as You Might Think | Wallace Marshall |
| 2/16/12 | Mina Bissell, LBNL | Why don't we get more cancer? The proposed role of the microenvironment in tissue specificity and breast cancer | Crystal Nyitray, Student |
| 2/23/12 | Amy Palmer, University of Colorado | Developing fluorescent tools for live cell imaging | Xiaokun Shu |
| 3/1/12 | Rami Hannoush | Chemical tools to perturb and image Wnt signaling | Danica Galonic Fujimori |
| 3/15/12 | Harmit Malik, Fred Hutchinson Cancer Center | Genetic conflicts: the usual suspects and beyond | John Gross |
| 4/5/12 | Ian Wilson, Scripps | Broad neutralization of HIV and influenza viruses | Bob Stroud |
| 4/12/12 | Michelle Chang, UC Berkeley | Building new chemical function in living organisms | Jack Taunton, Kevan Shokat |
| 4/19/12 | Alan Engleman, Farber Cancer Center | Retroviral integrase function and drug resistance mechanisms | Bob Stroud, HARC Sponsored |
| 4/26/12 | Howard Hang, Rockefeller | Chemical Reporters for Protein S-Palmitoylation in Cell biology and Innate Immunity | Danica Galonic Fujimori |
| 5/3/12 | Russ Altman, Stanford | The emerging network of data for linking genes and drugs | Chris Wen, Giacomini Lab, Computational Student Group |
| 5/17/12 | Jennifer Lippincott-Schwartz, NIH | Mitochondria, metabolism and cell cycle control: an imaging perspective | Amanda Silber and Si-Han Chen, Students |
| 5/24/12 | Ira Mellman, Genentech | Next Generation Approaches to Basic Cell Biology & Drug Discovery | Justin Rettenmaier, Wells Lab |
| 5/31/12 | Jim Ferrell | Dissecting the Mitotic Trigger | Wendell Lim |
| 5/31/12 | Jim Ferrell | Dissecting the Mitotic Trigger | Wendell Lim |
| 5/31/12 | Jim Ferrell, Stanford | Dissecting the Mitotic Trigger | Wendell Lim |
| Date | Speaker | Topic | Host |
|---|---|---|---|
| 9/30/10 | Ehud Isacoff, UC Berkeley | Pam England | |
| 10/14/10 | Quincey Justman, BP Alum | Kevan Shokat | |
| 10/21/10 | Amy Keating, MIT | Tanja Kortemme | |
| 10/28/10 | Bill De Grado, Braisted Talk | ||
| 11/18/10 | Bonnie Bassler, Princeton | Joe Kliegman | |
| 12/2/10 | Lei Wang, Salk Institute | Jack Taunton | |
| 1/13/11 | David Case, Rutgers | Kollman Lecture | Tom James |
| 1/20/11 | Hening Lin, Cornell | Danica Galonic & Jack Taunton | |
| 1/27/11 | Adrian Elcock, University of Iowa | Andrej Sali | |
| 2/3/11 | Erik Winfree, Caltech | Felix Moser, Voigt Lab | |
| 2/17/11 | Jonathan Eisen, UC Davis | Peter Skewes Cox and DeRisi Lab | |
| 2/24/11 | Ning Zheng, University of Washington | Jack Taunton | |
| 3/3/11 | Charalampos Kalodimos, Rutgers | Gross Lab, Robin Aglietti | |
| 3/17/11 | David Price, University of Iowa | HARC Center, Alan Frankel | |
| 4/14/11 | Mark Yeager, University of Virginia | HARC Center, Yifan Cheng | |
| 4/21/11 | CANCELLED: Niles Pierce, Caltech | Hana El Samad | |
| 4/27/11 | Chris Chen, U Penn | Tejal Desai and Sai Duriseti | |
| 4/28/11 | Bill Noble, University of Washington | Genevieve Erwin, Pollard Lab | |
| 5/5/11 | Eduardo Perozo, University of Chicago | David Julius | |
| 5/12/11 | Bruce Roth, Genentech | Brian Shoichet | |
| 5/19/11 | TBA | ||
| 5/26/11 | Alexander Van Oudenaarden, MIT | ||
| 6/2/11 | Linda Hsieh-Wilson, Caltech | Al Burlingame and Samuel Myers |
| Date | Speaker | Topic | Host |
|---|---|---|---|
| 10/1/09 | Jeremy Wilbur, Clements Recipient | Clements Distinguished BP Award Talk: Mechanisms for Scaling the Mitotic Spindle | |
| 10/15/09 | Alice Ting, MIT | Orion Weiner Lab, Sheel Dandekar | |
| 10/22/09 | Bill Jorgensen, Yale | Matt Jacobson | |
| 10/29/09 | Mark Mayer, NIH | Dan Minor | |
| 11/19/09 | Niko Grigorieff, Brandeis | Yifan Cheng | |
| 12/3/09 | Rachelle Gaudet, Harvard | Lily Jan | |
| 1/14/10 | James Berger, UC Berkeley | Dan Minor | |
| 1/21/10 | Andy McCammon, UCSD | Ken Dill | |
| 2/11/10 | Gerald Joyce, Scripps | Mike Lopez and Kevan Shokat | |
| 2/24/10 | Louise Jonson, Oxford | Bob Stroud, HARC Sponsored | |
| 2/25/10 | W.E. Moerner, Stanford | Matt Jacobson | |
| 3/11/10 | Angela Gronenborn, University of Pittsburgh | John Gross, HARC Sponsored | |
| 3/18/10 | Susan Taylor, UCSD | Matt Jacobson and Jim Wells | |
| 4/1/10 | Daniel Herschlag, Stanford | Babbitt Lab, Michael Hicks | |
| 4/15/10 | Jon Ellman, UC Berkeley | Charly Craik | |
| 4/22/10 | Edward Holmes, Penn State | Andino Lab, Cecily Burrill | |
| 4/29/10 | Peter Sorger, Harvard | Philip Merksamer, Papaz Lab | |
| 5/13/10 | Phil Cole, Johns Hopkins | Danica Galonic Fujimori | |
| 5/20/10 | Danny Tawfik, Weizmann Institute of Science | Brian Shoichet | |
| 5/27/10 | Erik Sorensen, Princeton | Brian Shoichet | |
| 6/3/10 | Eric Gouaux, OHSU | Rob Edwards |
| Date | Speaker | Topic | Host |
|---|---|---|---|
| 10/2/08 | David Savage | Clements Talk: The Carbon Cycle at a Molecular Level: Design Principles of Cyanobacterial and Yeast Metabolism | |
| 10/16/08 | Jamie Williamson, Scripps | Ribosome assembly: watching a machine assemble in vitro and in cells using mass spectrometry | S. Floor |
| 10/23/08 | Bruce Cohen, LBNL-Biological Nanostructures Facility of the Molecular Foundry | Smart Nanoparticles and the Future of Bioimaging | Lily Jan |
| 10/30/08 | Ruben Gonzalez, Columbia | Coupling of ribosome and tRNA dynamics during translation elongation | |
| 12/11/08 | A. Joshua Wand, University of Pennsylvania | The dark energy of proteins: Conformational entropy and its contribution to molecular recognition by proteins | C. Mcclendon |
| 1/15/09 | James Chou, Harvard | The Proton Channels of Influenza Virus | John Gross |
| 1/29/09 | Tom Muir, Rockefeller | Testing the Histone CodeHypothesis Using Synthesis | |
| 1/30/09 | Benoit Roux, University of Chicago | QB3/iPQB Invitational Speaker Series | Dill and Jacobson Labs |
| 2/12/09 | Richard Friesner, Columbia | Computational Modeling of Protein-Ligand Interactions: Successes, Challenges, and Prospects. | Matt Jacobson |
| 2/19/09 | Chris Miller, Brandeis | Chloride transporters and chloride channels all mixed up | Dan Minor |
| 2/27/09 | Sumit Chanda, Burnham Institute | Global Analysis of HIV host-pathogen interactions using RNAi | Frankel Lab |
| 3/12/09 | Bryan Roth, UNC, Chapel Hill | Synthetic and chemical biological approaches for modulating neuronal signaling in vivo | Brian Shoichet |
| 3/13/09 | Uri Alon, Weizman Institute of Science | QB3/iPQB Invitational Speaker Series | El Samad Lab |
| 3/19/09 | James Chen, Stanford | Chemical probes of embryonic signaling and patterning | |
| 3/20/09 | Jeff Kelly, Scripps Research Institute | QB3/iPQB Invitational Speaker Series | Shoichet Lab |
| 4/2/09 | Joachim Frank, NYU | Ribosomal Dynamics during Translation | Rebeca Choy |
| 4/16/09 | Wes Sundquist, University of Utah | The Biochemistry of HIV Budding | Alkan Frankel |
| 4/23/09 | Vern Schramm, Albert Einstein College of Medicine | Enzymatic Transition States: Drugs and Dynamics. | Danica Galanic Fujimori |
| 4/24/09 | Ian Haworth, USC | QB3/iPQB Invitational Speaker Series | Sali Lab |
| 4/30/09 | Deborah Hung, Harvard | ||
| 5/14/09 | TBA | Braisted Lecture | |
| 5/21/09 | Annelise Barron, Stanford | Robust, non-natural Aupeptoid, Au mimics of antimicrobial peptides for potent, selective bacterial pathogen killing | Ken Dill |
| 5/28/09 | Andy McCammon, UCSD | ||
| 5/29/09 | Aviv Regev, Broad Institute | QB3/iPQB Invitational Speaker Series | Weissman Lab |
| 6/12/09 | Steven Boyd, University of Calgary | QB3/iPQB Invitational Speaker Series | Majumdar Lab |
| Date | Speaker | Topic | Host |
|---|---|---|---|
| 10/11/07 | Nick Endres, UC Berkeley | Clements Talk: Using artificial lipid membranes to gain insights into the structure and function of signaling proteins in the EGFR/Ras signaling network | D. Agard |
| 10/18/07 | Justin Gallivan, Emory University | Reprogramming Bacteria with Small Molecules and RNA | P. England |
| 10/25/07 | Jack Szostak, Harvard Medical School | Braisted Lecture: Towards the Design and Synthesis of an Artificial Cell | C. Craik and J. Wells |
| 11/1/07 | Peter Wright, Scripps | Exploring the protein energy landscape: Disorder, dynamics, and protein function | S. Miller |
| 11/15/07 | Paul Hergenrother, University of Illinois | Using small molecules to identify novel targets for the treatment of cancer | J. Taunton |
| 11/29/07 | David Baker, U Washington | Novel enzyme catalysts, rapid structure determination, and pushing the limits of folding and design with a multiplayer online computer game | J. Wells |
| 12/13/07 | David Deamer, UC Santa Cruz | Nanopore analysis of DNA | K. Dill |
| 12/20/07 | Lewis Kay, University of Toronto | Seeing the invisible by solution NMR spectroscopy | T. James |
| 1/3/08 | Rob Phillips, Caltech | How Cells Decide What to Eat and Where to Go | W. Marshall |
| 1/10/08 | Tom Knight, MIT | R. Williams | |
| 1/17/08 | Tom Wandless, Stanford | A General Solution to the "Problem" of Chemical Genetics | J. Taunton |
| 1/24/08 | Gaudenz Danuser, Scripps | Integration of mechanical and chemical signals in cell migration deciphered by global fluctuation analysis | W. Marshall |
| 2/14/08 | Eric Siggia, Rockefeller University | Predicting the course of evolution | H. Li |
| 2/21/08 | Susan Marqusee, UC Berkeley | K. Dill | |
| 2/28/08 | James Inglese, NIH Chemical Genomics Center | Integrative Technologies Enabling Chemistry and Biology as a Public Resource for Chemical Probe and Drug Discovery | B. Shoichet |
| 3/13/08 | Gavin MacBeath, Harvard University | ||
| 3/20/08 | Ned Wingreen, Princeton | Modeling the chemotaxis network of E. coli | C. Tang |
| 4/17/08 | Tudor Oprea, University of New Mexico | From Digital to Experimental Bioactivity: Exploring novel estrogen receptors | B. Shoichet |
| 4/24/08 | Richard Ebright, Rutgers | Single-molecule analysis of transcription | G. Narlikar |
| 5/1/08 | Vishva Dixit, Genentech, Inc. | The Inflammasome & Deubiquitinases in Innate Immune Signaling | J. Wells |
| 5/15/08 | Rachel Brem, UC Berkeley | Expression variation and regulatory feedback | K. Dill |
| 5/22/08 | Jagesh Shah, Harvard Medical School | Biophysical measurements of mitotic checkpoint signaling: How cells prevent chromosome loss | W. Marshall |
| 5/27/08 | Gary Ruvkun, Harvard University | ||
| 5/29/08 | Brian Chait, Rockefeller University | Protein Interactions as a Window into Cellular Function | A. Krutchinsky |
| 6/5/08 | Gerald Crabtree, Stanford | Designing small molecules to regulate protein interactions |
| Date | Speaker | Topic | Host |
|---|---|---|---|
| 10/12/06 | Mathew Francis, UC Berkeley | New chemical tools for site-selective protein modification | P. England |
| 10/19/06 | Adrian Keatinge-Clay, UCSF | Dissecting, deciphering, and designing polyketide assembly lines | R. Stroud |
| 10/26/06 | Christopher Walsh, Harvard | Andrew Braisted Lecture, Halogenases: Natural product tailoring enzymes | C. Craik |
| 11/2/06 | Ron Weiss, Princeton | Synthetic biology: from bacteria to stem cells | C. Voigt |
| 11/16/06 | Jay Keasling, UC Berkeley | Engineering microorganisms for production of inexpensive, effective, anti-malarial drugs | C. Craik |
| 11/30/06 | Sarah O'Connor, MIT | Biosynthesis of new alkaloids in periwinkle | K. Shokat |
| 12/14/06 | Maurizio Pellecchia, Burnham Institute | A million little pieces: Fragment based approaches to drug discovery | M. Jacobson |
| 1/11/07 | David Weitz, Harvard | Reconstituted networks as models of cell mechanics | W. Marshall |
| 1/18/07 | Richard H. Kramer, UC Berkeley | Engineering light-activated ion channels for remote control of neuronal activity | R. Edwards |
| 1/25/07 | Edward Egelman, University of Virginia | Polymorphic perversity in polymers: The biological role of multiple subunit interfaces in helical filaments | D. Mullins |
| 2/1/07 | Christina Smolke, Caltech | Engineering molecular sensors for probing and programming cellular systems | H. El-Samad |
| 2/22/07 | Alice Ting, MIT | New protein labeling methodology and application to single molecule imaging of receptor trafficking with quantum dots | J. Wells |
| 3/1/07 | Lorena Beese, Duke | An integrated view of DNA polymerization and repair | R. Stroud |
| 3/15/07 | Wilfred van der Donk, University of Illinois | Chemistry and biology of ianthionine synthesis | J. Taunton |
| 4/12/07 | David Tirrell, California Institute of Technology | Non-canonical amino acids in protein engineering and proteomic analysis | P. England |
| 4/19/07 | Brenda Bass, University of Utah | dsRNA binding proteins in RNA editing and RNA interference | J. Gross |
| 4/26/07 | Adrian Gross, Northwestern | Structural aspects of potassium channel function | B. Shoichet |
| 5/10/07 | Pei Zhou, Duke University Medical Center | From novel antibiotics to fast NMR | J. Gross |
| 5/17/07 | Melissa Jurica, UCSC | Spliceosome structure by cryo-EM reconstruction | G. Narlikar |
| 5/24/07 | Phil Baran, Scripps | The catalytic cycle of discovery in total synthesis | A. Renslo |
| 5/31/07 | William Bialek, Princeton | Physics problems in early embryonic development | R. Fletterick |
| 6/7/07 | Luc Jaeger, UC Santa Barbara | Exploring folding, assembly and design principles of RNA as a proto-language | A. Frankel |