Adam Abate
Professor, Bioengineering & Therapeutic Sciences
Research summary: Microfluidic technologies for ultrahigh-throughput single cell analysis
Professor, Bioengineering & Therapeutic Sciences
Research summary: Microfluidic technologies for ultrahigh-throughput single cell analysis
Professor, Bioengineering & Therapeutic Sciences
Research summary: Deciphering the role of gene regulatory sequences in human biology and disease
*DEI/Mentorship Training Verified 2022
*UCSF Inclusive Mentor/Manager Training 2023
Professor, Pharmaceutical Chemistry
Research summary: Systems pharmacology and quantitative cell biology for drug discovery in cancer, intestinal and neurodegenerative diseases
*DEI/Mentorship Training Verified 2022
Research summary: The Andrews Lab focuses on determining the causal pathways that underlie the development of Alzheimer’s disease and related dementias (ADRD) by applying statistical genetic and genetic epidemiological approaches to large genetic & phenotypic datasets. Currently funded NIH-NIA and Alzheimer’s Association projects include (1) identifying causal risk factors for ADRD using genetic correlations, polygenic risk scores, and mendelian randomization; (2) understanding the role of mitochondrial genomics in ADRD pathogenesis; and (3) evaluating ancestry specific effects of AD genetic variants on AD endophenotypes.
*UCSF Inclusive Mentor/Manager Training 2023
Professor and Chair, Pharmaceutical Chemistry; Co-Director, Small Molecule Discovery Center, Pharmaceutical Chemistry
Research summary: Chemical biology of protein-protein interactions and small-molecule drug discovery using biophysical and biological approaches
*DEI/Mentorship Training Verified 2022
*UCSF Inclusive Mentor/Manager Training 2023
*The 4 Touchstones of a High-Functioning Mentoring Relationship Training 2024
Research summary: Pharmacology of drugs for HIV, malaria, and tuberculosis
Associate Professor in Residence, Surgery
Research summary: Genetics and Clinical Predictors of Drug Toxicities.
Professor, Bioengineering & Therapeutic Sciences
Research summary: Hepatic Physiology and Metabolism
*DEI/Mentorship Training Verified 2022
Professor in Residence
Research summary: Our research program focuses on understanding how aberrant signal transduction networks promote cancer and on defining the evolutionary forces that shape cancer initiation, progression, and molecular therapeutic response and resistance.
Associate Professor, Medicine
Research summary: Genetics approaches to study of the biology of the liver in health and disease
*DEI/Mentorship Training Verified 2023
Research summary: Pharmacogenomics and Genetic Epidemiology of Pulmonary Diseases
Professor, Pediatrics, and Institute Director, Baker Computational Health Sciences Institute, Chief Data Scientist, University of California Health
Research summary: In memoriam: https://chancellor.ucsf.edu/news/remembering-atul-butte-md-phd
https://chancellor.ucsf.edu/news/remembering-atul-butte-md-phd
Bioengineering & Therapeutic Sciences
Research summary: My lab studies how DNA is translated into life and how genetic mutations can lead to disease using cutting-edge computational and experimental techniques.
*The 4 Touchstones of a High-Functioning Mentoring Relationship Training 2024
Professor, Bioengineering & Therapeutic Sciences
Research summary: Using the tools of computer science and statistics to address problems in evolution, genetics, and biomedicine
*DEI/Mentorship Training Verified 2022
*Supporting Learners in Distress 2024
*The 4 Touchstones of a High-Functioning Mentoring Relationship Training 2024
Assistant Professor, Medicine, Medicine
Research summary: We are a translational cancer biology lab interested in identifying targetable synthetic lethal interactions, designing surface protein targeting therapeutics and understanding resistance mechanisms in cancer.
Assistant Professor, Neurology & Institute for Neurodegenerative Diseases
Research summary: Mechanisms and pharmacology of neurodegenerative diseases and innate immunity
*DEI/Mentorship Training Verified 2022
*UCSF Inclusive Mentor/Manager Training 2023
Professor, Gladstone Institute of Cardiovascular Disease
Research summary: Combining the tools of molecular biology, genetics, bioinformatics, and physiology to answer fundamental issues in pharmacology.
ryan.corces@gladstone.ucsf.edu
Assistant Professor, Gladstone Institutes
Research summary: Functional epigenomics to decipher the gene regulatory underpinnings of neurodegeneration
*DEI/Mentorship Training Verified 2022
*UCSF Inclusive Mentor/Manager Training 2023
willow.coyote-maestas@ucsf.edu
Assistant Professor, Bioengineering & Therapeutic Sciences
Research summary: We build and apply scalable mechanistic approaches to learn how membrane proteins underlie our physiology, what goes awry in disease, and how to better treat these diseases with therapeutics.
*The 4 Touchstones of a High-Functioning Mentoring Relationship Training 2024
Professor, Pharmaceutical Chemistry
Research summary: Protein engineering, mutagenesis, heterologous gene expression, enzyme mechanisms and inhibitor design.
*DEI/Mentorship Training Verified 2022
*The 4 Touchstones of a High-Functioning Mentoring Relationship Training 2024
Assistant Professor
Research summary: Combining genome editing and protein/cell engineering to address translational bottlenecks, with a special focus on hematopoietic stem cells and blood disorders.
*DEI/Mentorship Training Verified 2023
Assistant Professor, Clinical Pharmacy, Clinical Pharmacy
Research summary: Dr. Deitchman’s research program focuses on HIV and infectious disease clinical and translational pharmacology studies to inform drug development with an emphasis on trials to cure HIV. Based in the UCSF Drug Research Unit, a Center for AIDS Research Pharmacology core, which she codirects since 2022, her lab engages a multidisciplinary team of clinician-scientists and researchers here at UCSF and across international collaborative networks to design, execute, and analyze clinical studies in people with HIV. Since the start of the COVID-19 pandemic she has also been engaged in understanding immune responses following infection and vaccination across diverse cohorts and is now supports pharmacology studies of novel therapeutics for long COVID.
Research summary: CRISPR-Cas9 genome editing
Assistant Professor, Radiology & Biomedical Imaging
Research summary: Discovery and application of new biomarkers in oncology with molecular imaging
*DEI/Mentorship Training Verified 2022
*The 4 Touchstones of a High-Functioning Mentoring Relationship Training 2024
Professor and Chair, Bioengineering and Therapeutic Sciences Department, Bioengineering & Therapeutic Sciences
Research summary: Determining how engineering protein conformational ensembles change in response to chemical, physical, and genetic perturbations using structural, computational, and evolutionary approaches
*DEI/Mentorship Training Verified 2022
*Supporting Learners in Distress 2024
*The 4 Touchstones of a High-Functioning Mentoring Relationship Training 2024
Associate Professor in Residence, Institute for Neurodegenerative Diseases
Research summary: Targeting protein-protein interactions in the molecular chaperone complexes to understand protein homeostasis and treat protein misfolding diseases
*DEI/Mentorship Training Verified 2022
*The 4 Touchstones of a High-Functioning Mentoring Relationship Training 2024
Professor, Bioengineering & Therapeutic Sciences
Research summary: Molecular mechanisms of nucleosides transporters and organic cations, and pharmacogenomics
Assistant Prof In Res-Hcomp, Hematology/Oncology
Research summary: The Goga Lab seeks to understand how oncogenes reprogram the cell cycle, small RNAs and metabolism to drive tumorigenesis. Using a variety of model systems we seek to identify novel tumor vulnerabilities and develop anti-cancer therapeutics.
*The 4 Touchstones of a High-Functioning Mentoring Relationship Training 2024
Core Investigator, Arc Institute; Associate Professor, Biochemistry & Biophysics
Research summary: Cancer Systems Biology and Translational Genomics
Professor, BTS, Biopharm Sciences
Research summary: Brain Development Maintenance and Function; Therapeutic Discovery for Neurodegenerative, Neurodevelopmental, and Neuropsychiatric Disorders
*DEI/Mentorship Training Verified 2022
*The 4 Touchstones of a High-Functioning Mentoring Relationship Training 2024
Professor
Research summary: Human population genomics, computational and statistical inference, and analysis of genome resequencing data.
*DEI/Mentorship Training Verified 2022
*Supporting Learners in Distress 2024
Assistant Professor, Gladstone Institute
Research summary: Developing innovative mRNA vaccine and nanoparticle-based drug delivery technologies for cancer and infectious diseases.
Assistant Professor, Institute for Human Genetics
Research summary: Engineering and understanding gene regulation; combinatorial functional genomics; tissue biology.
Assistant Professor, Hematology & Oncology
Research summary: Cancer genomics, cancer disparities, prostate cancer, cellular immortality/mechanisms and genomics of telomere maintenance, cancer computational biology
*Supporting Learners in Distress 2024
Associate Professor – Department of Medicine – Experimental Medicine
Research summary: The Javid lab is focused on how leveraging understanding of the fundamental biology of Mycobacterium tuberculosis, and its interaction with the host, can be used for better tuberculosis treatments. The Javid lab is also interested in understanding and developing tools to reduce tuberculosis treatment times.
*UCSF Inclusive Mentor/Manager Training 2023
*Supporting Learners in Distress 2024
*The 4 Touchstones of a High-Functioning Mentoring Relationship Training 2024
Professor, Cellular & Molecular Pharmacology
Research summary: Structure/function studies of proteins kinases and their signaling networks
*DEI/Mentorship Training Verified 2022
Research summary: How age, stress and pH changes affect protein homeostasis and contribute to sporadic and familial neurodegenerative disorders
*DEI/Mentorship Training Verified 2023
*Supporting Learners in Distress 2024
Research summary: Mechanisms and therapies for retinal degenerations using advanced imaging techniques, cell and molecular biology, pharmacology and biophysics
*DEI/Mentorship Training Verified 2022
*UCSF Inclusive Mentor/Manager Training 2023
*The 4 Touchstones of a High-Functioning Mentoring Relationship Training 2024
Professor, Biochemistry & Biophysics
Research summary: Bioinformatics, genome sequence analysis, gene regulation
Associate Professor, Dermatology
Research summary: Dermatology and Human Genetics
Professor, Cellular & Molecular Pharmacology
Research summary: Cellular Signaling Systems
Assistant Professor, Neurological Surgery
Research summary: I am an Assistant Professor in the Department of Neurological Surgery at University of California, San Francisco (UCSF). Our lab focuses on identifying molecular mechanisms mediating immune suppression and evasion in brain tumors, with the goal of developing novel immunotherapeutics for these diseases. My recent research identified that protein phosphatase 2A negatively regulated T cell and macrophage mediated anti-tumor immunity, and further demonstrated that pharmacological inhibition of PP2A synergized with PD-1 blockade in multiple type of resistant tumors including glioblastoma. Based on those findings, a Phase I/II trial (NCT03027388) of PP2A inhibitor in recurrent glioblastoma is ongoing.
Associate Professor, Pharmaceutical Chemistry
Research summary: The Manglik lab studies the molecular basis of transmembrane signaling using integrative techniques in structural biology, biophysics, pharmacology, and protein engineering.
*DEI/Mentorship Training Verified 2022
Associate Professor, Microbiology & Immunology
Research summary: Quantitative biology research lab that uses systematic high-throughput and synthetic approaches to conquer fundamental problems in understanding gene function in health and disease.
*DEI/Mentorship Training Verified 2022
*The 4 Touchstones of a High-Functioning Mentoring Relationship Training 2024
Research summary: Genetic and molecular approaches in cardiometabolic disease risk and response to treatment
*DEI/Mentorship Training Verified 2022
Professor
Research summary: Developing effective immunotherapy for adult and pediatric patients suffering from brain cancer
Research summary: Improving pharmacological regimens for the prevention and treatment of cardiovascular disease through approaches in pharmacogenomics and pharmacoepidemiology
*DEI/Mentorship Training Verified 2022
ASSOC PROF IN RESIDENCE- FY, Gladstone Institute
Research summary: We are interested in how viruses interact with the host cell; through these interactions we hope to gain new insight into cellular processes and the viral life cycle. Currently, we focus on three pathogens—the human immunodeficiency virus (HIV-1), Zika virus, and the hepatitis C virus (HCV)—and three cellular processes—lipid droplets, transcriptional elongation, and immune reprogramming. Our research is relevant for efforts to eradicate HIV from patients, to alleviate fatty liver disease in chronic HCV infection, and suppress autoimmunity in patients with Type 1 Diabetes.
Associate Professor, Departments of Medicine and Biostatistics & Epidemiology
Research summary: Clinical trial design, adaptive trial designs, biostatistics, epidemiology, clinical drug development, infectious diseases.
Benioff Professor in Children's Health, Pediatrics
Research summary: The Piao lab aims to understand cell-cell interactions during brain development and disorders.
Professor, Epi & Biostats, Gladstone Institutes
Research summary: Comparative genomics, metagenomics, evolution, machine-learning, multivariate statistics
*DEI/Mentorship Training Verified 2022
*Supporting Learners in Distress 2024
Senior Investigator at Gladstone Institutes Professor in the Department of Urology at UCSF, Gladstone Institutes
Research summary: "Studying the mechanisms of HIV transmission and persistence, and the role of T cells in chronic human diseases"
Neurology
Research summary: Signal Transduction, Molecular Neurobiology of Addiction
*DEI/Mentorship Training Verified 2022
Assistant Professor, Medicine
Research summary: Breast organoid cultures, development of breast cancer prevention strategies, inflammatory breast cancer therapies
*DEI/Mentorship Training Verified 2022
Professor, Bioengineering & Therapeutic Sciences
Research summary: Biomedical devices, Micro/nano technology, Organ-on-chip, Sensors
*DEI/Mentorship Training Verified 2022
Professor, Bioengineering & Therapeutic Sciences
Research summary: Computation grounded in the laws of physics and evolution to study the structure and function of proteins
Professor, BTS, Bioengineering & Therapeutic Sciences
Research summary: Clinical and translational pharmacology, computational methods and modelling, drug development for global health, stratified medicine
*DEI/Mentorship Training Verified 2022
Professor, Pharmaceutical Chemistry
Research summary: Discovery, design, and synthesis of biologically small molecules and elucidation of their modes of action
*DEI/Mentorship Training Verified 2022
*Supporting Learners in Distress 2024
*The 4 Touchstones of a High-Functioning Mentoring Relationship Training 2024
Professor, Medicine, Medicine
Research summary: Mechanisms of action and resistance to targeted therapeutics in blood cancers, understanding molecular mechanisms of oncogene addiction
Associate Professor, Neurology
Research summary: Investigate genome function using functional genomics, iPSC models, and CRISPR screens.
*DEI/Mentorship Training Verified 2022
Professor & Chief, Pulmonary & Critical Care
Research summary: In vivo function of integrins and molecular basis of lung diseases
*DEI/Mentorship Training Verified 2022
Professor, Pharmaceutical Chemistry
Research summary: Molecular docking, structure-based inhibitor discovery, G Protein Coupled Receptors, colloidal aggregation and phospholipidosis in drug discovery and formulation, drug discovery for analgesia and psychiatric disorders.
*DEI/Mentorship Training Verified 2022
Professor, Pediatrics; Acting Director, Bakar Computational Health Sciences Institute
Research summary: Develop integrative computational methods and apply these approaches in the context of disease diagnostics and therapeutics
*DEI/Mentorship Training Verified 2023
Assistant Professor, Epidemiology & Biostatistics
Research summary: We primarily develop methods and theory to understand how evolution shapes the genetic architecture of complex traits at different biological scales, but we are also broadly interested in any biological puzzles that present interesting computational or statistical challenges.
Assistant Professor, Otolaryngology, Otolaryngology
Research summary: Development and mechanistic investigation of cancer immunotherapies.
alejandro.sweet-cordero@ucsf.edu
Pediatrics
Research summary: Genomics of pediatric sarcomas and lung cancer, discovery of novel targets for cancer therapy, translational genomics.
*UCSF Inclusive Mentor/Manager Training 2023
Research summary: My primary interest is identification of genetic determinants of drug response through modern methods aimed at addressing pharmacogenomics research and translating that information into new diagnostics and treatment strategies at point-of-care.
catherine.tcheandjieu@gladstone.ucsf.edu
Assistant Professor, Gladstone Institutes
Research summary: Genetic architecture of diseases in diverse populations
https://gladstone.org/people/catherine-tcheandjieu-gueliatcha
Associate Adjunct Professor, Epidemiology & Biostatistics
Research summary: Integrative genomic studies of complex disease in diverse populations
Associate Professor, Medicine
Research summary: Genetics of Metabolic Diseases
Professor, Laboratory Medicine
Research summary: Personalized medicine, breast oncology
Associate Professor, Psychiatry
Research summary: Complex genetic mechanisms in autism using human data and iPSC models
*DEI/Mentorship Training Verified 2023
Professor, Neurology
Research summary: Mouse models for tumors of the nervous system
*DEI/Mentorship Training Verified 2022
Professor, Pharmaceutical Chemistry
Research summary: Small molecule drug discovery; drug mechanisms as they relate to apoptosis and cancer.
*DEI/Mentorship Training Verified 2022
Assistant Professor, Laboratory Medicine
Research summary: Quantitative proteomics for target discovery + cellular therapy engineering for cancer
*DEI/Mentorship Training Verified 2023
*Supporting Learners in Distress 2024
Assistant Professor, Department of Clinical Pharmacy and Department of Pediatrics Division of Hematology/Oncology, Clinical Pharmacy
Research summary: *The 4 Touchstones of a High-Functioning Mentoring Relationship Training 2024
Professor, Laboratory Medicine
Research summary: Cardiac biomarkers, analytical, toxicology, pharmacogenomics and antibodies against COVID-19 infection and vaccinations.
Professor, Pharmaceutical Chemistry
Research summary: Drug discovery, cancer drug resistance, neurodegeneration, high-throughput imaging, machine learning, organoid models of disease
*DEI/Mentorship Training Verified 2022
Associate Professor, Departments of Dermatology and Pathology
Research summary: Role and function of oncogenes and tumor suppressors in the evolution of melanoma.
*DEI/Mentorship Training Verified 2022
Research summary: Elucidating the relationship between genes, brain structure, and behavior
*DEI/Mentorship Training Verified 2022
Associate Professor, Bioengineering & Therapeutic Sciences
Research summary: The Zhao Lab advances drug development and regulatory science through cutting-edge research in pharmacometrics, drug delivery modeling, and artificial intelligence (AI)-based tools that will closely impact drug development and regulatory decision-making.
Professor, Medicine, Internal Medicine
Research summary: Application of Population Genetics to the Study of Complex Traits in Humans
